Soeharyo H, Margawati A, Setyawan H and Djokomoeljanto
IDD concept is not the same with endemic goiter concept, that the disorder influence to physical and mental’s growth development, from fetus to adult. In the other side, the symptoms can’t be seen clearly, which difficult to be observed without special observation. There are great variation on IDD disorder from goiter, endemic cretin to minimal brain damage. But that disorder can be prevented well by using iodine adequately and continuously. The main hindrance in the field including: 1) Iodine vehicle choices, although generally the main choice is iodinized salt and the alternative choice is iodine solution in oil 2) Reaching guarantee on IDD’s high susceptible group, like school-children, pregnant women, breast-feeding women, eligible women.3) Continuity programme, remembering the main IDD problem is the result of iodine deficiency area, that need management continuously. (more…)
Iodine deficiency disorders (IDD) is still one of public health nutrition problems in many countries, including Indonesia. Through various efforts the IDD prevalence is reducing, but still unsatisfactory.
It is widely accepted that iodine deficiency is caused mainly by low availability of iodine in the soil. However, role of some other substances is of attentions for the last decade, including goitrogenic substances. Other micronutrients might play important role. The paper is concentrating on the relationship of selenium and iodine deficiency.
Selenium is one of essential micronutrients. The requirement is quite low and (theoretically) easy to be toxic in higher doses. It can be found in seafood, organ and small amount in plants. It is consumed as inorganic selenium, selenomethio-nine and selenocycteine. The absorption is passive in a high proportion, hence it does not play in homeostasis of selenium. (more…)
Johan S. Masjhur
Iodine excess and iodine deficiency may trigger thyroid autoimmune response. Iodine excess exacerbates the thyroid autoimmunity as iodine induced hyperthyroidism which frequently found in iodine deficiency areas, meanwhile the iodine induced hypothyroidism may be found in normal iodine intake areas. This mechanism is mediated through thyrocid toxiety process and increasing thyroglobuline immunogenity. (more…)
Iodine is a trace element present in the human body, and it is essential substrate for the synthesis of the thyroid hormone. Iodine deficiency during pregnancy may results the increase risk of spontaneous abortion, premature birth and early infant death, as well as transient neonatal hyperthyrotropinemia. This deficiency also has a deleterious effect on the development of the infant’s tone, since may cause hypotonia both in the extremities and axial muscles during early life. The deleterious effect is also found for the postural responses (late infant reflexes) but not for the neonatal (so-called primitive) reflexes. This developmental delay does not persist during the course of infancy since catch up can be attained by the age of 6 months. (more…)
Abdul Razak Thaha, Djunaidi M. Dachlan dan Nurhaedar Jafar
Until recently, risk factors related to coastal goiter in Maluku are still inconclusive. This study was carried out to identify the predominant risk factors of IDD in Maluku. The study was conducted in two group of islands (“Gugus Pulau”) with highest prevalence and two “Gugus Pulau” non-endemic areas. Study subjects were schoolchildren and randomly chosen from those who participated in a mapping study of IDD prevalence in 1996 consist of 117 and 200 for case and control groups respectively. (more…)